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KMID : 0356720050210030174
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Journal of the Korean Society of Coloproctology
2005 Volume.21 No. 3 p.174 ~ p.177
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Perianal Extramammary Paget´s Disease Associated with an Anal Duct Adenocarcinoma -A Case Report-
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Lee Kang-Youn
Yun Min-Young
Choi Sun-Keun
Heo Yoon-Seok
Lee Kun-Young
Kim Sei-Joong
Cho Young-Up
Ahn Seung-Ick
Hong Kee-Chun
Shin Suk-Hwan
Kim Kyung-Rae
Woo Ze-Hong
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Abstract
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Extramammary Paget´s disease occurs commonly on the external female genitalia and rarely occurs in the perianal region. Recently, we experienced a case of perianal extramammary Paget´s disease associated with an anal duct adenocarcinoma. The patient was a 60-year-old man. The perianal skin lesion was eczematous and encircled the anus. A wide-excision, split-thickness skin graft and temporal T-loop colostomy were performed. Histopathologically, the tumor was a well-differentiated anal duct adenocarcinoma. There was a prominent pagetoid spread of about 6×4 cm. The tumor cell was positive for carcinoembryonic antigen, but the paget cell was negative. The patient was treated with radiation therapy and with single 5-FU chemotherapy six times. Five months later, the perianal region was nearly normal. J Korean Soc Coloproctol 2005;21:174-177
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KEYWORD
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Paget´s disease, Extramammary, Anal neoplasm, Adenocarcinoma
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